منابع مشابه
Jump-starting kinesin
When it is not actively transporting cargo, conventional Kinesin-1 is present in the cytoplasm in a folded conformation that cannot interact effectively with microtubules (MTs). Two important and largely unexplored aspects of kinesin regulation are how it is converted to an active species when bound to cargo and the related issue of how kinesin discriminates among its many potential cargo molec...
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Magnetic stimulation as used in studies of the human brain may not merely disrupt cognitive functions, but also enhance them. The direction of the effect may depend on the frequency of stimulation as much as the area of the brain that is stimulated.
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Vaccination with tumor antigens causes tumor regression in some melanoma patients despite negligible expansion of vaccine-specific T cells. Vaccination may instead result in the expansion of T cells specific for tumor antigens not contained in the vaccine, thus facilitating tumor regression, according to two articles from Pierre Coulie and colleagues on pages 241 and 249. Tumor-specific T cells...
متن کاملJump-starting Concept Map Construction with Knowledge Extracted from Documents
Online documents provide a rich information resource for aiding the generation of concept-map-based knowledge models, but analyzing resources to select concepts and links is a time consuming task. This paper describes ongoing research on harnessing the information in unstructured textual documents, using information extraction algorithms, to generate a preliminary version of a concept map from ...
متن کاملJump-starting immune reconstitution after stem cell transplantation
Recipients of hematopoietic stem cell transplants (HSCT) are at high risk for opportunistic infection. Bacterial and certain fungal infections predominate during the immediate posttransplantation period when patients are neutropenic and have abnormal mucosal barriers. But HSCT recipients continue to be at risk for infections even after their neutropenia and mucositis have resolved. Particularly...
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ژورنال
عنوان ژورنال: Clinical Journal of the American Society of Nephrology
سال: 2020
ISSN: 1555-9041,1555-905X
DOI: 10.2215/cjn.06570520